Estudio de la interacción de nanomateriales con antígenos: una aproximación sistemática para el desarrollo de nanovacunas (NANOVAC)

Reference: SAF2011-30337-C02-02
Funding Entity: Ministry of Science and Innovation
Coordinator: María José Alonso (University of Santiago de Compostela)
Principal Investigator of the sub-project: Dr. África González-Fernández
Duration: 01/01/2012 – 31/12/2014

Working group:

Dr. Rosana Simón Vázquez
Andrea Fernández Carrera
Andrea Hernández Fernández
Dr. Silvia Lorenzo Abalde (Former member)
Dr. Mercedes Peleteiro Olmedo (Former member)
Dr. Daniel Pérez Estévez (Former member)
Ángela Davila Graña (Former member)


The main objective of this project was to understand the mechanisms undergoing on the immunogenicity of several Nanoparticles (Nps) intended as antigens delivery systems in the development of nanovaccines. Since Nps in biomedical applications could have clear beneficts, there are some crucial aspects such as toxicity and immunogenicity that must be carefully addressed. The results obtained in this project provided valuable information for nanovaccines design, allowing a more rational design to achieve biocompatible, alternatively administered and more efficient vaccines.

Associated research lines: , .