Several researchers, including África González, have published a letter in Nature Methods in which they express their DISAGREEMENT with the recommendation issued by the European Commission to stop using mice to develop monoclonal antibodies and instead use alternative methods, which they think is not scientifically justified.
All related information in:
EURL ECVAM Recommendation on Non-Animal-Derived Antibodies
Better antibodies without using animals
Non-animal-derived monoclonal antibodies are not ready to substitute current hybridoma technology